Hangzhou Pharmaceutical Client Visits Bolaike: 5㎡ Pharmaceutical Freeze Dryer Wins Favor with GMP Standards and Energy-Saving Advantages

Recently, Jiangsu Bolaike Refrigeration Technology Development Co., Ltd. (hereinafter referred to as "Bolaike") received a pharmaceutical enterprise client from Hangzhou. The client had previously learned about Bolaike's pharmaceutical freeze-drying experiments using vials and was deeply impressed by the finished product state—complete material morphology inside the vials, loose and delicate structure, and ideal moisture content control. This time, the client made a special trip to Bolaike's Changzhou production base for an on-site inspection.

The focus of the client's visit was Bolaike's 5-square-meter medium-sized freeze dryer. This equipment is specifically designed for the pharmaceutical industry and strictly follows pharmaceutical GMP standards. The chamber is made of food-grade 316 stainless steel, which is corrosion-resistant and easy to clean, meeting the hygiene standards of pharmaceutical companies. The equipment is equipped with a stoppering function, allowing vial stoppering and sealing to be completed directly under vacuum after freeze-drying, achieving fully aseptic operation. At the same time, the equipment can be configured with online cleaning and sterilization functions. After connecting to an external cleaning station, the system automatically completes the cleaning process, effectively avoiding cross-contamination between batches.

In terms of process details, the equipment has an excellent appearance with a strong stainless steel texture. All piping and wiring are wrapped in stainless steel, making the overall appearance neat, easy to clean and maintain, with wiring layout clear at a glance. In terms of core configuration, the vacuum pump uses the German-imported Leybold brand, offering fast pumping speed and stable operation. The equipment is equipped with residual cold recovery and an intelligent control system, reducing comprehensive energy consumption by 20% to 30% compared with conventional equipment. Based on a five-year operating cycle, the electricity cost saved can offset half of the equipment's purchase cost.

The entire equipment occupies less than 10 square meters and adopts a square cabin structure design, making it convenient for laboratory and production workshop layout. Using vials as containers, a single batch of Φ22mm specification can hold approximately 40,000 vials, with a loading capacity of 50 kg, capable of meeting the medium-scale production capacity needs of pharmaceutical enterprises.

As a technology-leading enterprise in China's food freeze-drying equipment field, Bolaike has accumulated more than 200 patents and is the only freeze-drying equipment enterprise in the country to have won the highest science and technology awards of both Shandong and Jiangsu provinces. The company's technical accumulation can be traced back to 2003. Its products cover a full range of models with freeze-drying areas from 0.5 square meters to 200 square meters, widely used in food, pharmaceutical, and biotechnology fields. Bolaike's subsidiary, Xinshidai Freeze-Drying Technology Research Institute, has established joint training bases and strategic cooperative relationships with universities such as Jiangnan University and China Agricultural University.

If you have needs for pharmaceutical freeze-drying equipment, you are welcome to leave a comment below for consultation. Bolaike can provide full-process technical support from equipment selection to process development.